Best Enzymatic Cleaners 2021

Last Updated on by Micheal Nathan


Rug Doctor 05039Enzymatic Cleaner


Great value for money

Works fantastic

Quite delightful

Excellent cleaning

Rocco & Roxie Professional Strength Stain & Odor Eliminator


100% satisfaction guaranteed

Certified gentle and safe product

Enzyme activated

Upholstery and carpets

Mister Max Unscented Anti Icky Poo Odor Remover


Easy elimination of cat urine

Used in heavily stained areas

Light liquid product

Presence of live bacteria

Bubbas Super Strength Commercial Enzyme Cleaner


Suitable for most surfaces

Satisfaction guarantee

Carpet and Rug Institute certified

Sunny & Honey Enzyme Cleaner


Comes in a convenient spray bottle.

Gentle on both fabric and skin.

Designed to neutralize unpleasant odors.

Effectively tackles stubborn stains.

Nature’s Miracle Urine Destroyer


Infused with a natural citrus scent.

Effective on ingrained stains.

Features a bio-enzymatic formula.

Can be used on a wide range of surfaces.

Simple Solution Extreme Pet Stain and Odor Remover, 945 ml


Professional strength formula

Safe for use around pets and children

The clean, refreshing scent

Life Miracle Enzymatic Cleaner


No heavy-duty chemicals

All-natural ingredients

Versatile product

Multi-enzyme formula

TriNova Enzymatic Cleaner


100% natural cleaner

Free for using anywhere

Safe around pets and kids

100% satisfaction guaranteed

Amaziing Solutions Enzymatic Cleaners (Gallon)


Neutralizes odor

Better than the traditional chemical

No need of scrubbing

Versatile cleaner


Are you willing to get rid of the odor in your home from your pet’s urine? This guide is here to offer you a solution. We would be looking at the best enzymatic cleaners. If your interested in getting one, you should go through this guide, you’ll be glad you did if you do.

Why Enzymatic Cleaners?

Enzymatic cleaners leverage the power of good bacteria to expunge the most stubborn stains and odors. That happens with zero toxic contamination in your home. Also, the detergents are gentle on the fabrics.

No cleaner in the market is effective enough in cleaning pet’s pee-stained couches. Some end up bleaching the fabrics, but all that changed when you try enzymatic cleaners.

Reasons to try Enzymatic Cleaners:

  • Non-toxic

One defining feature for enzymatic cleaners is that they don’t have a chemical formulation whatsoever. Their bacterial makeup is non-toxic as well. They are biodegradable and harmless.

  • Eco-friendly

The non-toxic ingredients of these cleaners make them safe for the environment. Using enzymatic cleaners is the least you can do in the fight for a greener planet.

  • Deep cleaning

Enzymatic cleaners work slowly, that is something you will have to accept. But, I think you will appreciate their results; these cleaners offer an in-depth cleaning action, sipping further into the tiniest crevices.

  • Long-lasting

The cleaning action doesn’t stop even after you rinse and take your gloves off. The enzymes stay behind, working for the next 24 hours to remove all dirt and odor.

Enzymatic cleaners can be used in:

  • Bathrooms and kitchens

It’s time to put down the bleach and the pungent odors it leaves behind. An enzymatic cleaner can break down the stains on your kitchen sink, toilets, tubs, and bathroom floors just as powerfully as chemical cleaners.

  • Cleaning carpets and floors

Enzymatic cleaners are effective against pet stains on rugs and carpets. The enzymes in these cleaners quickly break down the protein composition of the stains, eventually stripping them out entirely along with their odors.

  • Laundry and fabrics

Enzymatic cleaners can also help in cleaning clothes and other upholstery.  You only have to pre-soak them overnight for an effective de-staining/de-greasing.

NB: Your enzymatic cleaner can perform better when used with lukewarm water.



The most important feature that a buyer must look for while purchasing the enzymatic cleaner is it should be non-toxic. There should not be any chemical compound present in it. The cleaner should be harmless, and biodegradable.

Method of Application

It’s quite natural that you would be looking for an enzymatic cleaner that is easy to use. The cleaners that come in a spray bottle are quite convenient for usage especially when you can adjust the nozzle according to your wish. It means that there is no need to go close to the stain to eliminate it effectively.

Purchasing an enzymatic cleaner that comes in pour bottles can give you a great deal of savings compared to the spray bottles. But, you need to go close while cleaning the stain with the cleaner.

It is better to opt for a cleanser that comes in a pour bottle along with a spray bottle so that you can transfer the liquid every time you want to use it.

Deep Cleaning

Before purchasing an enzymatic cleaner, you must first understand that enzymatic cleaners consume time to clean the stain. But, the most important that you must know is they offer in-depth cleaning of the stain.


After rinsing, as well as removing the gloves, the cleaning action does not stop here. The enzyme will stay behind for at least 24 hours that helps in eliminating the odor and dirt from the area.

The Odor of the Enzymatic Cleaner

It depends upon the personal taste of the person whether or not you like the smell of the enzymatic cleaner. It is a good idea to spend time and determine which cleaner to opt for. Selecting a fragrance-free cleaner is a better option if you do not like the smell of any of the cleaner.


There are commercial, industrial, and domestic levels of concentration when you need to select the enzymatic cleaners. Using too high concentration can degrade the fabric or can corrode the skin as well.

On the other hand, if the formulation is too weak, then you need to use more amount of cleaner for effective stain removal.


Rug Doctor 05039Enzymatic Cleaner


It is one of the enzymatic cleaners that can be used by rabbit owners who have rabbits at home. The product works fantastic and comes with an enhanced formulation.

  • Achieves better results
  • Ineffective cleaning of pet protein stains
  • Power ingredients
  • Ineffective spot remover
  • Used on carpets
  • Deep cleaning
  • Easy to use

Rocco & Roxie Professional Strength Stain & Odor Eliminator


The Rocco & Roxie Professional Strength Stain & Odor Eliminator has been certified by the Carpet and Rug Institute. This means that you can be sure that it will be safe to use on carpets and other fabrics. Because it is free from chlorine, you will not have to worry about the color of your carpet being affected.

This product can be used to effectively eliminate lingering stains from both urine and vomit. It works to break down the acid in animal urine to neutralize it. Simply allow the spray to soak into your carpet for ten minutes, and the urine odor will be removed.

As a bonus, this spray does not leave any type of residue behind. There will be no need to rinse it away after it has done its job. The Rocco & Roxie Professional Strength Stain & Odor Eliminator can be used on a wide range of surfaces, including hardwood floors.

  • Free from chlorine.
  • May cause respiratory irritation.
  • Does not leave behind a residue.
  • Comes in a convenient spray bottle.
  • Suitable for use on a wide range of surfaces.

Mister Max Unscented Anti Icky Poo Odor Remover


The name of this best Enzymatic Cleaner certainly makes it clear what this product has been designed for. In case you need it spelled out, Mister Max Unscented Anti Icky Poo Odor Remover is designed to tackle pet waste. This includes strong cat urine, stains, and dog odors.

This special formula can be sprayed directly on a wide range of different types of surfaces. Cat urine and other substances will quickly become a thing of the past. You are also likely to find that your pet is unlikely to urinate in the treated area in the future.

It should be noted that heavily stained areas may need to be treated more than once. If the stain has been on your carpet for a while, it is a good idea to let the spray soak in. However, once it has worked its magic, you will be left with a light and a refreshing perfume scent.

  • Suitable for use on various fabrics and wood.
  • May need to treat stains repeatedly.
  • Removes odors rather than masking them.
  • Boasts a light and refreshing scent.
  • Works on cat urine and dog odors.

Bubbas Super Strength Commercial Enzyme Cleaner


This formula uses naturally dormant bacteria which activate as soon as they come into contact with cat urine and other odors. The plus side of this means this cleaner retains its efficiency even when stored over time, while other odor removers using activated bacteria will have a much shorter shelf-life.

  • Comes in a convenient spray bottle.
  • Not powerful enough for tough stains.
  • Does not leave residue behind.
  • Safe to use on laundry.
  • Gentle on the skin.

Sunny & Honey Enzyme Cleaner


Sunny & Honey is another top enzymatic cleaner, completely removes all new and old pet stains from feces, urine, and vomit. Similar to other enzyme cleaners, it also destroys all harmful bacteria causes for a strong-bad urine smell.

Its multi-surface formula works better on the carpet, bedding, furniture, hardwood, litter boxes, cages, crates, leather, rugs, pet beds, and in-car upholstery. Though Sunny & Honey pet stain and odor miracle made for pet odors, it successfully works for human messes, mattress stains, even strong chemical odors.

It is safe for both pets and children to use because the natural enzymatic formula provides the safest way to clear all stains with odors. Moreover, this pet cleaner not only helps to remove odors but also pulls hard to remove blurs from clothes, carpets, and similar others.

  • The special quality ingredients easily eliminate hard stink from the carpet and other surfaces
  • Some pet owners don’t enjoy the smell
  • The multi-surface formula for carpet, hardwood, furniture, leather, rugs, and pet beds
  • The enzyme-based cleaner works well to remove stains and odors
  • 100% money back guaranty
  • Made in the USA

Nature’s Miracle Urine Destroyer


Nature’s miracle offers one of the most budget-friendly urine destroyer crafted with bio-enzymatic formula and strongly functional to eliminate stain and odor from clothes, carpets, furniture, and more. It ensures permanent elimination of strong pet urine odors, yellow stains, and sticky residue from any surface.

It can simply wipe away any soak stain of urine from the surface within five minutes and show better performance on both old and new spots. It has a multidimensional usage you can observe if used with patience.

  • Safe to use on floors, furniture, carpets, fabrics, and any other surface
  • This product contains chemicals to cause cancer
  • Spreads a light fresh scent after using
  • Helps to remove odor and stain easily
  • Featured with bio-enzymatic formula

Simple Solution Extreme Pet Stain and Odor Remover, 945 ml


This formula supposedly contains both Pro-Bacteria and enzymes.  That, therefore, makes it a likely powerful ally in the extermination of tough stains and pet urine odors. Because of pro-bacteria, its cleaning action could be faster than most enzymatic cleaners in the market.

Extreme Pet Stain and Odor Remover are recommendable for busy people who don’t have plenty of time to spend on cleaning floors and upholstery. However, note that its powerful concentration might not be gentle on your skin.

According to the manufacturers, the enzymatic cleaner is three times stronger than other detergents owing to its pro-bacteria formulation. It is safe for use on carpets, laundry, beddings, and upholstery.

  • Spray bottle for flawless delivery
  • It might leave a dull spot on your carpet
  • Can be used on a variety of fabrics and surfaces
  • Its high enzymatic concentration can cause skin irritation
  • The pro-bacteria formulation makes it extra-powerful

Life Miracle Enzymatic Cleaner


It is the best cleaner that contains all kinds of natural products to clean the stain and odor from the area and is considered to be of professional-grade.

  • Used in the washing machine
  • Requires scrubbing
  • Effective for any kind of stain
  • Ineffective cleaning
  • General go-to cleaner
  • Concentrated
  • Allergy-free

TriNova Enzymatic Cleaner


Even if the stain is quite old, this cleaner can help you in cleaning it. Along with the application being effortless, thanks to the convenient spray bottle. It also comes with an herbal scent and the product is quite invigorating and light.

  • Usage in kennel, Cage, mattress, carpets
  • The bottle straw is short
  • Increases professional strength
  • Stubborn stains cannot be eliminated
  • Eliminates older stain
  • Dissolves stain

Amaziing Solutions Enzymatic Cleaners (Gallon)


The amazing pet cleaner is considered to be one of the most effective cleaning products. The creator of the product has created an amazing cleaner to satisfy the customers by eliminating the dog urine stain.

It’s time to say goodbye to the regular floor cleaner which is not that effective as the pet stain cleaner. It uses an amalgamation of strong cleaning elements to eliminate the stain. You must use it carefully as you could end up with faded spots if you are not using properly.

  • Used in hardwood floors, carpet, and upholstery
  • Difficult to work with large containers
  • Powerful and refreshing cleaner
  • Fabrics can fade
  • Lifetime satisfaction results
  • Dissolves stains
  • Works quickly


As a pet owner, it is your moral duty to sort out the best suit odor eliminator to maintain a clean and fresh environment in your room. The best enzymatic eliminators always work instantly and destroy all harmful germs and remove bad odor to accumulate the best-mannered guy in the house.

So, take a moment to get the right one for you and conquer the war to keep your surroundings bad odor and stain free.